Browse Drugs


Please click on the alphabet below to browse the drugs by letter



ID Name Ref.ID Type Primary indication Orphan indications* Rare indication Common indication Source
Rx00079 Dapsone DB00250 Small-molecule Toxoplasmosis; immunodeficiency; Pneumocystis carinii pneumonia Dermatitis herpetiformis; acne vulgaris
FDA;
PubMed
Rx00080 Daunorubicin DB00694 Small-molecule Acute nonlymphiocytic leukemia (myelogenous, monocytic, erythroid); adult acute lymphocytic leukemia; juvenile acute lymphocytic leukemia Acute myeloid leukemia Acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid); acute lymphocytic leukemia
FDA;
PubMed
Rx00081 Decitabine DB01262 Small-molecule French-American-British myelodysplastic syndrome; myelodysplastic syndromes; refractory anemia; refractory anemia with ringed sideroblasts; refractory anemia with excess blasts; refractory anemia with excess blasts in transformation; chronic myelomonocytic leukemia Acute leukemia; chronic myelogenous leukemia; sickle cell anemia; acute myeloid leukemia French-American-British myelodysplastic syndrome; myelodysplastic syndromes; refractory anemia; refractory anemia with ringed sideroblasts
FDA;
PubMed
Rx00082 Dexamethasone DB01234 Small-molecule Corneal graft rejection; ocular inflammation; panuveitis Palpebral conjunctiva; bulbar conjunctiva; allergic conjunctivitis; acne rosacea; superficial punctate keratitis; herpes zoster keratitis; iritis; cyclitis; infective conjunctivitis; edema; inflammation; corneal injury; allergic otitis externa; purulent infective otitis externa; nonpurulent infective otitis externa
FDA;
PubMed
Rx00083 Dextran DB00893 Small-molecule Cystic fibrosis; recurrent corneal erosion Anaphylaxis; hypovolemic shock
FDA;
PubMed
Rx00084 Difluprednate DB06781 Small-molecule Endogenous anterior uveitis; traumatic anterior uveitis; panuveitis Inflammation; pain
FDA;
PubMed
Rx00085 Digitoxin DB01396 Small-molecule Ovarian cancer; soft tissue sarcoma; cystic fibrosis Cardiac arrhythmia; heart failure
FDA;
PubMed
Rx00086 Dimethyl sulfoxide DB01093 Small-molecule Scleroderma; intracranial pressure; head injury; traumatic brain coma; soft tissue injury; palmar-plantar erythrodysesthesia syndrome; drug resistant tuberculosis Interstitial cystitis
FDA;
PubMed
Rx00087 Doripenem CHEMBL491571 Small-molecule Bronchopulmonary infection; cystic fibrosis Intra-abdominal infections; urinary tract infections; pyelonephriti
FDA;
PubMed
Rx00088 Doxepin DB01142 Small-molecule Depression Insomnia, itch
FDA;
PubMed


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Dudley Laboratory
Department of Genetics and Genomic Sciences
Icahn Institute for Genomics and Multiscale Biology
Icahn School of Medicine at Mount Sinai
One Gustave L. Levy Place, Box 1498
Manhattan, New York City, NY
repurposedb@dudleylab.org