Browse Drugs


Please click on the alphabet below to browse the drugs by letter



ID Name Ref.ID Type Primary indication Orphan indications* Rare indication Common indication Source
Rx00145 Mannitol DB00742 Small-molecule Bronchiectasis; cystic fibrosis Acute renal failure; cerebral edema
FDA;
PubMed
Rx00146 Mazindol DB00579 Small-molecule Duchenne muscular dystrophy Obesity
FDA;
PubMed
Rx00147 Mecamylamine DB00657 Small-molecule Hypertension Attention Deficit Hyperactivity Disorder
FDA;
PubMed
Rx00148 Mecasermin DB01277 Biotech Pediatric growth failure; primary IGFD Amyotrophic lateral sclerosis; post-poliomyelitis syndrome; growth hormone receptor deficiency; antibody-mediated growth hormone resistance; isolated growth hormone deficiency I; short-bowel syndrome; small bowel resection; congenital dysfunction of the intestines; major burns; myotonic dystrophy Juvenile growth failure; severe, primary insulin growth factor-1 deficiency; growth hormone gene deletion
FDA;
PubMed
Rx00149 Medroxyprogesterone acetate DB00603 Small-molecule Immune thrombocytopenic purpura Amenorrhea; abnormal uterine bleeding; endometrial hyperplasia; metastatic endometrial carcinoma; renal carcinoma; endometriosis-associated pain
FDA;
PubMed
Rx00150 Melphalan DB01042 Small-molecule Multiple myeloma; non-resectable epithelial carcinoma of the ovary; Breast cancer; recurrent in-transit metastatic melanoma of the extremities; unresectable in-transit metastatic melanoma of the extremities; amyloidosis Metastatic melanoma of the extremity; hematopoietic stem cell transplantation; cutaneous melanoma; ocular melanoma; uveal melanoma; neuroendocrine tumors Multiple myeloma; non-resectable epithelial carcinoma of the ovary
FDA;
PubMed
Rx00151 Mepivacaine DB00961 Small-molecule HIV-associated neuropathy; postherpetic neuralgia Anesthesia
FDA;
PubMed
Rx00152 Mesalamine DB00244 Small-molecule Active mild ulcerative colitis; active moderate ulcerative colitis; pediatric ulcerative proctitis Adult ulcerative colitis; active ulcerative proctitis
FDA;
PubMed
Rx00153 Mesna CHEMBL975 Small-molecule Hemorrhagic cystitis Urotoxicity Ifosfamide-induced hemorrhagic cystitis
FDA;
PubMed
Rx00154 Methotrexate DB00563 Small-molecule Cancer Psoriasis; Rheumatoid Arthritis PubMed


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Dudley Laboratory
Department of Genetics and Genomic Sciences
Icahn Institute for Genomics and Multiscale Biology
Icahn School of Medicine at Mount Sinai
One Gustave L. Levy Place, Box 1498
Manhattan, New York City, NY
repurposedb@dudleylab.org