Rx00039 - Beractant


Name:
Beractant
Rx ID:
Rx00039
Validation Level:
Phenomic Similarity:
0.666
Reference ID:
CHEMBL1201624
Primary Indications:
Infant Respiratory Distress Syndrome
Orphan Indications:
No annotated orphan indications.
Rare Indications:
Respitory failure; meconium aspiration syndrome; newborn persistent pulmonary hypertension; pneumonia; sepsis
Common Indications:
Infant Respiratory Distress Syndrome; hyaline membrane disease
Drug Interactions:
No annotated drug interactions in DrugBank.
Food Interactions:
No annotated food interactions in DrugBank.

Interactive Drug Target Network

Interactive Bipartite Drug Repurposing Graph

Rx00039
Primary Indication
Secondary Indication

Disease prevalence from Electronic Health Records

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Disease A Disease B A∩B A∩¬B B∩¬A Odds-Ratio P-Value Adjusted P-Value
infant Respiratory Distress Syndrome pneumonia 366 2237 36519 18.077 1.21E-300 3.89e-297

Shared Genetic Architectures of Disease Pairs

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Disease A Disease B Adjusted P-Value Shared Gene IDs
INFANT RESPIRATORY DISTRESS SYNDROME PNEUMONIA 8.17e-26 ABCB1, ACE, ADRB2, CYP3A5, GSTM1, GSTP1, GSTT1, IFNG, IL10, IL12A, IL1A, IL8, MBL2, MMP1, MMP12, MMP9, NOS3, SERPINE1, SFTPA1, SFTPA2, SFTPB, SFTPC, SFTPD, TNF, VEGFA

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Dudley Laboratory
Department of Genetics and Genomic Sciences
Icahn Institute for Genomics and Multiscale Biology
Icahn School of Medicine at Mount Sinai
One Gustave L. Levy Place, Box 1498
Manhattan, New York City, NY
repurposedb@dudleylab.org